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Cancer.gov •

India’s First Homegrown CAR T-Cell Therapy

February 7, 2024,
by Linda Wang


In 2015, Alka Dwivedi, then a graduate student at the Indian Institute of Technology (IIT) Bombay, began wondering whether a CAR T-cell therapy could be made in India.

At the time, several CAR T-cell therapies—a type of immunotherapy in which a person’s T cells are modified in a laboratory to selectively kill cancer cells—were being tested in clinical trials in the United States. And although CAR T-cell therapies looked to be promising trea...
Cancer.gov •

New breast cancer tissue biomarker

Researchers at the National Institutes of Health (NIH) have identified a series of changes in the architecture and cell composition of connective tissues of the breast, known as stromal tissue, that is associated with an increased risk of developing aggressive breast cancer among women with benign breast disease, and poorer rates of survival among women with invasive breast cancer. This process, which they call stromal disruption, could potentially be used as a biomarker to identify women with b...
Cancer.gov •

Cancer risk decreases with more physical activity

In a prospective cohort study of more than 85,000 adults in the United Kingdom, researchers at the National Institutes of Health (NIH) and University of Oxford found that individuals who engaged in light- and moderate-to-vigorous-intensity daily physical activity had a lower risk of cancer than individuals who were more sedentary. The findings, published March 26, 2025, in British Journal of Sports Medicine, are among the first to evaluate the cancer risk reduction associated with light-intensit...
Chordoma Foundation •

How families of children affected by chordoma are driving hope and…

Photo: Sloane SwantonChordoma in children and young adults can be aggressive, and better treatments are urgently needed for this unique population. At the Chordoma Foundation, we’re advancing pediatric chordoma research and providing free, personalized guidance to help families access expert care and treatment for children diagnosed with this disease — all made possible by the generosity and fundraising efforts of families affected by chordoma.
This Childhood Cancer Awareness Month, we’re proud...
Patient Power •

Antibiotic Resistant Superbugs Always a Risk for Cancer Patients

As if battling cancer weren’t challenging enough, an invisible threat is making cancer care even more complicated: antimicrobial-resistant superbugs that are increasingly hard to treat. A large study published in May 2025 in The Lancet Oncology found that people with cancer who received care in outpatient settings – like a doctor’s office or surgical center – were much more likely to get drug-resistant bacterial infections compared to people without cancer treated in similar settings.“That surpr...
Chemical & Engineering News •

Opening Up About Stress In Graduate School

Like many graduate students, Karen Chiang entered her Ph.D. program full of enthusiasm, and she looked forward to earning her scientific wings.




But instead, graduate school became associated with some of the lowest points in her life, because of the overwhelming stress and self-doubt she experienced. “I had a very difficult time seeing myself in a positive light,” says Chiang, who earned a Ph.D. in chemistry recently and is now teaching...
Cancer.gov •

Proteogenomics Study Identifies Cancer Drug Targets

September 11, 2024,
by Linda Wang


Most targeted cancer drugs work by blocking proteins in or on cancer cells that help tumors grow. But the process of identifying promising proteins to target can be painstaking and often leads to false starts and dead ends.

Now, a team of researchers from the United States and China has identified hundreds of proteins that appear to be either promising targets for existing drugs or leads for the development of new cancer treatments. 

The...